![]() This correlation may be useful for anticipating the need for repeat plasmapheresis. Serum viscosity and electrophoresis are recommended before and after plasmapheresis in order to correlate viscosity and M-spike with patient symptoms. ![]() Hyperviscosity syndrome can also occur in multiple myeloma patients.īecause the ability of a monoclonal protein to cause hyperviscosity is affected by its concentration, molecular weight, and aggregation, sera with concentrations of monoclonal IgM greater than 4 g/dL, IgA greater than 5 g/dL, or IgG greater than 6 g/dL should be tested for hyperviscosity. The most common cause of serum hyperviscosity is the presence of large concentrations of IgM monoclonal proteins, and Waldenstrom macroglobulinemia accounts for 80% to 90% of hyperviscosity cases. The test result gives us a tentative or partial indication of viscosity. For ease of construction work and quick results, we have carried out the Marsh Funnel Viscosity Test at the site. In this method, the obtained viscosity of bentonite slurry is not as accurate. Funduscopic examination reveals dilation of retinal veins and flame shaped retinal hemorrhages. Marsh Cone Viscosity test is also known as the Funnel viscosity test. Hyperviscosity may be manifested by nasal bleeding, blurred vision, headaches, dizziness, nystagmus, deafness, diplopia, ataxia, paresthesias, or congestive heart failure. Viscosity is the property of fluids to resist flow.
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